Scott has appeared in numerous television series such as Dark Angel, Joey and CSI: Miami. In 2002 she appeared as Helena Kyle/The Huntress on The WB television drama series Birds of Prey. The series premiered October 9, 2002. Despite the weekly ratings of 7.6 million viewers and the network's largest audience in the 18–34 demographic at the time, the series was cancelled. Thirteen episodes were produced in total.
In 2006 it was announced she has signed on as a series regular on Jericho as Emily Sullivan. The show ran on CBS from September 20, 2006 through March 25, 2008. It was initially canceled after its first full season due to poor ratings. While a fan campaign was able to convince the network to bring the show back for a seven-episode second season, it was canceled for a second time after that run. In May 2010, Scott appeared as Dana Hutton, in an episode of the CBS series NCIS.
Scott made her screen debut in a minor role as Gigolo Jane in AI Artificial Intelligence in 2001. She has since then appeared in numerous films such as S.W.A.T. (as Jim Street's Girlfiriend), Walking Tall and Strange Wilderness.
In 2005 she appeared in the role of Amanda in Columbia Pictures action film Into the Blue. In 2008 she starred in film Strange Wilderness as Cheryl. In 2009 she starred alongside John Cena in 12 Rounds.
